Cerebral Exercise, done using Cerebra TurboBrain technology, increases angiogenesis and synaptogenesis through neurovascular coupling

The Physiological and Neurological basis of Cerebra TurboBrain

  • Frontal Lobes are positioned at the foremost region of the brain.
  • The prefrontal cortex forms the “essence” of Frontal Lobes that sets us apart from other primates.
  • The prefrontal cortex regulates executive functions which govern our behavior. Executive functions are high-level cognitive abilities that influence basic abilities, motor skills, memory, attention, decision-making and planning.
  • Evidence suggests that there is a reduction in cerebral blood flow to the region of prefrontal cortex for individuals suffering from diseases in which cognitive functions are compromised such as ADHD, Alzheimer’s disease etc. See the images of a SPECT scan below. The normal brain (on the left) shows normal blood perfusion, denoted by an abundance of yellow color. The brain scan on the right, of a person suffering from Alzheimer’s, shows pervasive hypo-perfusion (low perfusion) all around, denoted by blues and greens.
  • Cerebra TurboBrain provides a drug free alternative for the treatment of the above disorders, as well as a means for training and reconditioning one’s brain for optimizing its level of performance.
  • The Cerebra TurboBrain device measures and provides a feedback about the blood flow dynamics and metabolic activity in specifically targeted brain modules.
  • Neurovascular coupling, a mechanism that explains the activation of brain matter whenever there is increase in the above measurements.
  • In other words, whenever there is an increase in neuronal activity (which happens when the brain engages in some specific mental task) there is a rapid localized increase in cerebral blood flow.
  • Blood brings glucose & oxygen to fuel neuronal firing in your brain conducive to the metabolic requirement and neuronal activity of a particular brain module at a given point in time.
  • With regular brain exercise, blood flow to the brain increases, the brain grows larger and its abilities greater.
  • Researched-based studies have proven this procedure increases one’s I.Q. (intelligence quotient) by 1.2 points per session. Imagine the possibilities!

Here is what the original inventor of this technology, the late Dr.Hershel Toomim, had to say:

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Using HEG trains the subject to increase blood flow to a targeted area of the brain. You have probably tried shining a flashlight through your hand and have seen the dark side light up. Our tissues, flesh and bone, are translucent. It’s not dark in there. In the sunlight, if you were in there with your brain, you could read a newspaper by that light. In HEG a light is shone on your brain through the translucent scalp and skull.

A spectrophotometer device is worn on the head. Flashing red and infrared lights are shown in the Figure as one optode. The light collection amplifier is another type of optode. It responds to the returned light that is reflected and refracted by the encountered tissue. These optodes are spaced 3 centimeters apart so as to conduct most of the available light at the depth of cortical tissue. As can be seen the application is very simple. Red, 660 nm, and infrared, 850 nm, lights are alternately shown on brain tissue. The graph below shows the large difference in red light tenuation between oxygen rich and oxygen starved hemoglobin whereas the infrared light is minimally changed. (Elwell 1999) A computer program receives a measure of each light color, calculates their ratio, and graphs the value for the patient to see, hear and alter. During the summer of 1994, it was discovered that the author could intentionally increase cerebral regional oxygenation. The computer graph responded to thoughts. Brain oxygenation increased merely by intensely willing it.

There are no known side effects for HEG treatments. Can’t remember? Can’t focus? Misplace things? Slow learning? Always tired? Turned around? These are some common physical brain problems. Healthy brains have adequate blood flow. Problem brains have insufficient blood flow to limited brain areas. Several brain areas are involved in whatever you do. Finding the affected areas is key. A non-invasive directed brain exercise is indicated.

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Further, to quote Glynn Blackett

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The Physiological Basis of HEG


One way to quantify brain activity is in terms of metabolic activity or metabolic rate. In fact this concept has widespread applicability in the field of neuroimaging. Metabolism is a cellular process in which “fuel” in the form of glucose or sugar is “burned” to release energy for use by the cell. The process consumes oxygen and creates carbon dioxide. Metabolic rate is the rate at which energy is used up.

When the brain is engaged in some mental task such as mental arithmetic, we expect that those regions of the brain directly involved in the task will use energy at a faster rate than other regions.

The human brain is extremely metabolically active. Although the brain makes up just 2% of body weight, it accounts for 20% of the body’s oxygen consumption and 25% of glucose consumption. In order to meet this energy demand, brain tissue has an extremely dense network of blood vessels and capillaries.

How do we measure metabolic rate? We can measure it indirectly, in a number of ways. Some of these ways rely on a phenomenon known as neurovascular coupling.

Neurovascular Coupling


Metabolic activity depends upon a supply of glucose and oxygen, which arrive via the bloodstream. Neurovascular coupling is a mechanism for matching blood flow to metabolic demand in the brain. This means that whenever there is a localized increase in neural activity (which happens when the brain engages in some specific mental task) there is a rapid localized increase in cerebral blood flow. A consequence of this response is that the blood in the active region becomes more oxygenated (i.e. the concentration of oxygen increases). The process is managed by cells called astrocytes: these are a common type of glial cell or support cell in the brain. The Prefrontal Cortex (PFC) is the region of the cortex (outer layer of brain) behind the forehead, and also above the eyeballs (on the underside of the brain). The PFC is a particularly important part of the brain, most highly evolved in humans, and sometimes described as the brain’s executive control centre. It plays a central role in purposive behavior – making decisions formulating and carrying out plans and intentions, and sticking to them in the face of distracting stimuli. It coordinates the brain resources needed to carry out these intentions, and evaluates actions in terms of their success or failure in meeting objectives.

The PFC is also strongly linked to motivation and emotion (these are of course connected). You can keep to a long-term plan (e.g. gaining a degree) by somehow holding in mind the good feelings connected to achieving that goal.

The PFC has the ability to inhibit other structures in the brain connected to emotions, enabling you to for example override a fear of heights when you need to climb a ladder.

Emotions are connected decision-making – it seems that the PFC arrives at decisions by in some way “imagining” the feelings that would result from each option.

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